Specification: 98% min
Appearance: White Powder
Molecular Formula: C18H19F3N2O4S2
Test Method: HPLC
WAY 316606 WAY 316606 is an sFRP-1 (protein associated with Frizzled protein) (Ki = 80 nM); an endogenous antagonist of the secreted glycoprotein Wnt. IC50 value: 80 nM (Kd); 0.65 uM (EC50) Target: sFRP-1 studies have shown that WAY 316606 binds to sFRP-1 with a K(D) of 0.08 microM and inhibits it with an EC (50) of 0.65 microM.roM.
Function of WAY 316606
WAY 316606 increased total bone area in a murine calvarial organ culture assay at concentrations as low as 0.0001 microM.